01 The AI scientist

Intelligence, held to the test of nature.

Rafati builds an AI scientist together with the autonomous laboratories where it works. Software forms a hypothesis, runs the real experiment, and learns from what the physical world returns. Knowledge is not something you read. It is something you make.

Based inLos Angeles, California
FocusThe physical sciences
MethodClosed-loop discovery
Founded2026

02 The thesis

New knowledge is made only when an idea meets the resistance of the real world.

The last decade of scientific AI leaned almost entirely on models trained on the text of the internet, a finite resource that the leading systems have now largely exhausted. The discoveries ahead will not be found on a page. They have to be produced, one experiment at a time, and read back from nature itself.

GB

A single experiment can return gigabytes of signal that exists in no paper, dataset, or archive. Our models read all of it.

24/7

Automated facilities run without a queue or idle bench time, compounding the dataset day after day.

Zero

Results thrown away. Every outcome is kept, including the negative results the literature almost never publishes.

03 The premise

Intelligence alone does not move science forward.

A model can reason beautifully and still discover nothing. Reasoning rearranges what is already known. Discovery requires contact with a world that can surprise you, and that is precisely what a language model, on its own, has never had.

So we do not stop at building smarter models. We build the places where those models can act: on real instruments, real materials, and real results. The model proposes, the laboratory performs, and reality decides. That verdict, kept and studied in full, becomes the teacher.

05 The discovery loop

How discovery happens here.

One full turn of the engine, in three movements. The model designs, the lab runs, and reality answers. Then the answer becomes the next question, faster than the turn before.

01

Hypothesize

aSet the goal. Choose a property worth chasing, then predict which materials or conditions might deliver it.
bScreen in simulation. Model the candidates first, ruling out dead ends before touching hardware.
02

Experiment

aHand off to the lab. The plan becomes instructions for real instruments, running around the clock.
bMeasure and keep everything. Gigabytes of signal per run, successes and failures alike, all recorded.
03

Learn

aCheck against reality. Physics is verifiable, so a result can be confirmed the way a proof or a program can.
bUpdate and iterate. Fold the data back in, sharpen the next hypothesis, and the dataset compounds.

06 Where this leads

The hardest problems are problems of materials.

We begin in the physical sciences because the signal is high, the work is fast, and the results are simulatable and verifiable. From there, automating the discovery of materials reaches into some of the most consequential questions there are.

01

Higher-temperature superconductors

Materials that carry current with minimal loss, closer to the temperatures of everyday life.

Energy
02

Better semiconductors

Including the chip heat-dissipation problems that hold back the hardware we depend on.

Compute
03

Practical nuclear fusion

Materials and designs that help bring a long-promised source of clean power within reach.

Power
04

Materials for space

Structures engineered to survive the punishing demands of leaving and living beyond Earth.

Frontier

07 Work with us

Let's discover something together.

If you are a scientist, an engineer, an industry partner, or a builder who wants ideas to meet reality, we would like to hear from you.